Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Visit old site
Home Print this page Email this page Small font size Default font size Increase font size
Users Online: 161
Year : 2016  |  Volume : 8  |  Issue : 6  |  Page : 243-249

Cardiovascular responses to an isometric handgrip exercise in females with prehypertension

1 Department of Recreation, Human Performance and Leisure Studies and Exercise Science and Human Nutrition Laboratory, Howard University Cancer Centre, Washington DC, USA
2 Department of Medicine, Division of Cardiology, Howard College of Medicine and Howard University Hospital, Washington DC, USA
3 Department of Internal Medicine, Howard University Hospital, Washington DC, USA
4 Department of Medical Pharmacology, AUA College of Medicine, Antigua and Barbuda; Manipal University, Manipal, Karnataka, India
5 Department of Behavioural Sciences and Neuroscience, AUA College of Medicine, Antigua And Barbuda
6 Department of Medical Physiology, AUA College of Medicine, Antigua And Barbuda

Correspondence Address:
Dr. Richard M Millis
Department of Medical Physiology, American University of Antigua College of Medicine, Jabberwock Beach Road,
Antigua And Barbuda
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1947-2714.185032

Rights and Permissions

Background: Hypertensive individuals are known to exhibit greater increases in blood pressure during an isometric handgrip exercise (IHE) than their normotensive counterparts. Aim: This study tests the hypothesis that, compared to normotensive individuals, prehypertensive individuals exhibit an exaggerated response to IHE. Materials and Methods: In this study, the effects of IHE were compared in matched prehypertensive vs. normotensive healthy African-American females. Six healthy young adult African-American female university students were screened in a physician's office for blood pressure in the range of prehypertension, systolic blood pressure (SBP) 120-139 mmHg and diastolic blood pressure (DBP) 80-89 mmHg. Six young adult African-American women were also recruited to serve as a healthy normotensive control group with SBP ≤119 mmHg and DBP ≤79 mmHg. Cardiovascular fitness was determined by peak oxygen uptake (VO 2 peak) measured during a progressive exercise test. Results: During the handgrip exercise, the prehypertensive group exhibited greater increases in SBP (from 139 ± 6 to 205 ± 11 mmHg, +48%) than the controls (from 132 ± 3 to 145 ± 3 mmHg, +10%); intergroup difference P < 0.001. The prehypertensive group also exhibited greater increases in DBP (from 77 ± 2 to 112 ± 5 mmHg, +46%) compared to the controls (from 72 ± 3 to 78 ± 4 mmHg, +8%); intergroup difference P < 0.001. The increase in systemic vascular resistance was also greater in the prehypertensive group (from 1713 ± 91 to 2807 ± 370 dyne.s.cm -5 , +64%) than in the controls (from 1668 ± 80 to 1812 ± 169 dyne.s.cm -5 , +9%); intergroup difference P < 0.05. Conclusion: These results suggest that blood pressure measurements performed during IHE may be a useful screening tool in evaluating prehypertensive individuals for antihypertensive treatments.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded630    
    Comments [Add]    
    Cited by others 7    

Recommend this journal