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Year : 2015  |  Volume : 7  |  Issue : 10  |  Page : 476-479

Diabetes insipidus: An unusual presentation of adenocarcinoma of the lung in a patient with no identifiable lung mass

1 Division of Hematology/Oncology, University of Cincinnati, Cincinnati, Ohio, USA
2 Division of Pathology and Lab Medicine, University of Cincinnati, Cincinnati, Ohio, USA

Correspondence Address:
Shuchi Gulati
Department of Internal Medicine, University of Cincinnati, 231 Albert Sabin Way, ML 0535, Cincinnati, Ohio-45220
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1947-2714.168677

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Context: Lung cancers are known to metastasize to unusual sites. Despite this knowledge often times the diagnosis of a primary lung cancer gets delayed especially when the patient presents without respiratory symptoms. Case Report: The patient discussed in our review is a 47-year-old female, smoker who had presented to several hospitals with months of headache, nausea and intermittent episodes of vomiting. She was noted to have hypernatremia due to diabetes insipidus and a pituitary lesion on her magnetic resonance images. The pituitary mass on biopsy was found to represent a metastatic focus from a primary lung adenocarcinoma. Conclusion: Clinicians should be aware of malignancies that are well known to metastasize to the posterior pituitary. Conversely, since not every patient presents with symptoms of metastasis, there is a need to recognize the clinical syndromes (e. g., diabetes insipidus-like symptoms or more subtle symptoms like cranial nerve palsies) associated with potential metastasis to the pituitary.

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