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Year : 2014  |  Volume : 6  |  Issue : 7  |  Page : 342-345

Sarcomatoid carcinoma of the lung: A model of resistance of chemotherapy

1 Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco; Jules Bordet Institute, Brussels, Belgium
2 Departments of Medical Oncology, National Institute of Oncology, Rabat, Morocco
3 Department of Pathology, Hassan Loboratory, Rabat, Morocco

Correspondence Address:
Imane Ouziane
Department of Medical Oncology, Jules Bordet Institute, Free University of Brussels, Brussels, Belgium, and Department of Medical Oncology, National Institute of Oncology, Quartier Irfane, Hay Riad, Morocco

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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1947-2714.136920

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Context: Lung tumors are very heterogeneous histological entities. Pulmonary sarcomatoid carcinoma is a subset of tumors characterized by specific histological features. Their poor prognosis compared to other lung tumors is due to limited responses to different types of chemotherapy. Case Report: We report two patients with sarcomatoid tumors: A 53-year-old woman and a 46-year-old man who presented respiratory symptoms: Dyspnea, cough, associated with a deterioration of general condition. Conclusion: Pulmonary sarcomatoid carcinomas remained an unexplored entity, despite their poor prognosis. Based on these cases, we will discuss the histological and immunohistochemical features of these tumors, as well as report their responses to different chemotherapy regimens used in the course of treatment.

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